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Helps prevent calcium and lime build-up in your HoMedics brand ultrasonic humidifier. Reduces mineral build-up and "white-dust" caused by hard water when used in ultrasonic humidifiers. Works with all HoMedics ultrasonic humidifiers with a capacity of one gallon and larger: UHE-OW14, UHE-WM85, UHE-WM65, UHE-CM25, UHE-CM45, UHE-OC1. Simply drop one cartridge into water tank. Replace cartridge every 30-40 fillings, depending on the water hardness. Includes 4 cartridges.